AiCuris, 4SC Discovery and CRELUX announce drug discovery collaboration
We are proud to offer our partners a great number of various assays developed and implemented by expert professionals. By integrating all project activities into one project management team, ChemDiv offers an excellent resource for efficient use of capital.
Unique design of these sublibraries provides a very robust way for early mini-SAR analysis for identification and confirmation of hit series, which then become seed templates for hit expansion, hit-to-lead exploration, and medicinal chemistry lead optimization. A robust screening platform encompassing automated liquid handling and multimode signal detection equipment have been assembled at ChemDiv to be able to provide access to screening assays for multiplicity of targets, such as receptors, enzymes, signaling pathways etc.
We have assembled a robust screening infrastructure to be able to work with targets of major therapeutics areas. Our technical park of Discovery Division includes:.
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ChemDiv has assembled a robust high throughput screening platform encompassing automated liquid handling and multimode signal detection equipment for assays to be ran in up to well plate formats. Multimode reading capability provides access to screening assays with multiplicity of targets, such as receptors, enzymes, signaling pathways etc. Toxic and potentially interfering use of organic solvents or surfactants is replaced by approaches that not only can provide good exposure in preclinical efficacy and toxicological examination, but also suggest approaches for eventual larger scale formulation pathways.
Its formulators typically utilize intermediates in milligram quantities, to enhance its characteristics for testing in in vitro and in vivo DMPK studies and for initial formulation. BioDuro has the ability to provide solutions related to increased solubility and bioavailability from preclinical drug discovery through final dosage form development and GMP manufacture. Using translational medicine to bridge the gap between research and applied science enables faster, more focused research and development and can reduce risks before making big investments in later development stages.
Since the molecule selected as a candidate may have multiple therapeutic uses, formulators must determine the use that can be most effectively and efficiently developed for clinical trials.
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Cyrus K. He held several senior level management positions in his ten-year career at Nichols Institute Diagnostics a division of Quest Diagnostics.
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As general manager and executive director at Ontogen, a small molecule discovery company, he managed operations of a subsidiary focused on high-throughput synthesis and purification of novel chemical compounds. LinkedIn www. Email cyrus. Keep up with our latest articles, news and events.
Plus, get special offers and more delivered to your inbox. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics, microfabrication techniqes, integrated proteomics technologies, high throughput screening, and fluorescence correlation spectroscopy methods.
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